How to cite item

Regulatory T cells and Th1/Th2 in peripheral blood and their roles in asthmatic children

   
@article{TP1335,
	author = {Yan-Li Yang and Yu-Qin Pan and Bang-Shun He and Tian-Ying Zhong},
	title = {Regulatory T cells and Th1/Th2 in peripheral blood and their roles in asthmatic children},
	journal = {Translational Pediatrics},
	volume = {2},
	number = {1},
	year = {2013},
	keywords = {},
	abstract = {Objective: To determine the changes in CD4+CD25+Foxp3+ regulatory T cells (Treg) and the Th1/Th2 ratio in peripheral blood of children with asthma, in order to investigate its association with asthma.
Methods: A total of 150 children with asthma were allocated into the acute phase group (n=94) and remission phase group (n=56) based on clinical manifestations. The acute phase group was subdivided into the mild group (n=54) and severe group (n=40). Flow cytometry was applied to determine CD4+CD25+Foxp+ Treg, CD4+IFN-γ+ Th1 and CD4+IL-4+ Th2 levels in peripheral blood of different groups, and the results were compared with normal children (control group, n=50).
Results: The Treg level was significantly lower in the asthma group than the control group (P},
	issn = {2224-4344},	url = {https://tp.amegroups.org/article/view/1335}
}