@article{TP1848,
author = {Hidehiko Narazaki and Takeshi Asano},
title = {Consideration of Glucocorticoids and Escherichia coli-derived L-asparaginase in the treatment of pediatric acute lymphoblastic leukemia},
journal = {Translational Pediatrics},
volume = {2},
number = {2},
year = {2013},
keywords = {},
abstract = {Glucocorticoids (GCs) are steroid hormones these are synthesized in the adrenal cortex. After binding to the nuclear glucocorticoid receptor (GR), activated GR complexes play a major role in immune system regulation by exerting a variety of effects such as inhibition of cyclooxygenase and inflammatory cytokines (IL-1, IL-2, IL-5, IL-6, INF-γ) synthesis, neutrophil induction, lymphocyte activation, etc. (1).},
issn = {2224-4344}, url = {https://tp.amegroups.org/article/view/1848}
}