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Changes in interleukin-17 and transforming growth factor beta 1 levels in serum and bronchoalveolar lavage fluid and their clinical significance among children with asthma

  
@article{TP2849,
	author = {Kun Jiang and He-Bin Chen and Ying Wang and Jia-Hui Lin and Yan Hu and Yu-Rong Fang},
	title = {Changes in interleukin-17 and transforming growth factor beta 1 levels in serum and bronchoalveolar lavage fluid and their clinical significance among children with asthma},
	journal = {Translational Pediatrics},
	volume = {2},
	number = {4},
	year = {2013},
	keywords = {},
	abstract = {Objectives:To investigate the changes in the levels of interleukin-17 (IL-17) and transforming growth factor beta 1 (TGF-β1) in serum and bronchoalveolar lavage fluid (BALF) and their clinical significance among children with asthma.
Methods: A total of 56 children with asthma were divided into moderate or severe asthma (n=37) and mild asthma groups (n=19) and 18 children without asthma were selected as the control group. Cells in BALF were counted under a microscope. The levels of IL-17 and TGF-β1 in serum and BALF were measured using enzyme-linked immunosorbent assay (ELISA).
Results: There were no significant differences in total cell count and percentage of macrophages between the two asthma groups and the control group (P>0.05). The percentages of neutrophils, eosinophils and epithelial cells in BALF were significantly higher in the two asthma groups than in the control group (P},
	issn = {2224-4344},	url = {https://tp.amegroups.org/article/view/2849}
}