@article{TP4260,
author = {Derya Özyörük and Taliha Öner and Yeşim Oymak and Hüseyin Tuğrul Çelik},
title = {Comparison of Doppler echocardiographic and tissue Doppler velocity data in beta-thalassaemia major with high and normal NTProBNP levels of children in the south-east region of Turkey},
journal = {Translational Pediatrics},
volume = {3},
number = {4},
year = {2014},
keywords = {},
abstract = {Background: It has been reported that N-terminal pro-brain natriuretic peptide (NT-proBNP) is early biomarker of iron- induced cardiomyopathy in β-thalassemia major (β-TM). In this study, we aimed to assess the Doppler echocardiographic, tissue Doppler velocity datas and clinical characteristics in β-TM patients with high and normal NT-proBNP levels who have normal systolic function.
Material and method: Fifty-eight β-TM patients who were on regular transfusion in every 3-4 weeks for more than one year and 20 healthy children were included into the study. According to NT-pro BNP levels, β-TM patients are divided in two groups. Group I: the patients with high NT-proBNP levels; Group II: the patients with normal NT-proBNP levels.
Results: The mean serum NT-proBNP levels were significantly increased in patients with β-TM compared to control group (P},
issn = {2224-4344}, url = {https://tp.amegroups.org/article/view/4260}
}