Bariatric surgery in adolescents—a vital treatment option
Editorial Commentary

Bariatric surgery in adolescents—a vital treatment option

Gitanjali Srivastava1,2,3,4 ORCID logo

1Division of Diabetes, Endocrinology & Metabolism, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA; 2Department of Surgery, Vanderbilt University School of Medicine, Nashville, TN, USA; 3Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN, USA; 4Vanderbilt Weight Loss Center, Vanderbilt University Medical Center, Nashville, TN, USA

Correspondence to: Gitanjali Srivastava, MD. Division of Diabetes, Endocrinology & Metabolism, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA; Department of Surgery, Vanderbilt University School of Medicine, Nashville, TN, USA; Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN, USA; Vanderbilt Weight Loss Center, Vanderbilt University Medical Center, 719 Thompson Lane, Suite 22200, Nashville, TN 37204, USA. Email: gitanjali.srivastava@vumc.org.

Comment on: Bruze G, Järvholm K, Norrbäck M, et al. Mental health from 5 years before to 10 years after bariatric surgery in adolescents with severe obesity: a Swedish nationwide cohort study with matched population controls. Lancet Child Adolesc Health 2024;8:135-46.


Keywords: Pediatric obesity; adolescent bariatric surgery; medical weight management; mental health; substance abuse disorders


Submitted Apr 25, 2024. Accepted for publication Jul 17, 2024. Published online Aug 08, 2024.

doi: 10.21037/tp-24-160


As a faculty of medicine specializing in adult and pediatric obesity care, I am compelled to address the critical issue of bariatric surgery in adolescents with severe obesity. The recent study (1) titled “Mental health from 5 years before to 10 years after bariatric surgery in adolescents with severe obesity: a Swedish nationwide cohort study with matched population controls” by Bruze et al. provides valuable insights into the impact of bariatric surgery on mental health outcomes in this vulnerable young population. The assumption that substantial weight loss from bariatric surgery will positively influence both short-term and long-term mental health in adolescents with severe obesity is questioned.

The study is the largest adolescent bariatric surgery prospective cohort from nationwide registries, which means it tracks the health outcomes of adolescents who have undergone bariatric surgery over a long period. This design allows for the evaluation of long-term effects, which is crucial as many studies tend to focus on short-term outcomes. The study provides robust evidence that psychiatric diagnoses and psychiatric drug prescriptions were more common among adolescents with severe obesity both pre- and post-bariatric surgery than among matched adolescents from the general population. The study also suggests that adolescents who undergo bariatric surgery do not necessarily have more mental health problems than their peers with severe obesity who do not undergo surgery. This finding is significant as it challenges common misconceptions about the mental health impact of bariatric surgery. Adolescents undergoing bariatric surgery also suffer from more substance abuse disorders than their peers in the general population as per the study (1). Research in adults also shows an increased risk of substance use disorder, particularly with alcohol, after bariatric surgery (2). This highlights the need for further research in post-bariatric maladaptive eating behavior and nutritional deficiencies. Overall, these findings underscore the complexity of treating severe obesity in adolescents and the importance of considering both the physical and mental health outcomes when evaluating the long-term effectiveness of bariatric surgery. As always, a comprehensive, patient-centered approach is key to ensuring the best possible outcomes for these young patients (3,4).


The weight of the matter

Severe obesity in adolescents is not merely a cosmetic concern; it is a complex medical disease with far-reaching consequences including cardiovascular morbidity and mortality (5). As we witness the rising prevalence of obesity-related comorbidities (6), we must explore evidence-based interventions that can transform lives. Bariatric surgery, once reserved for adults, has emerged as a vital treatment option for adolescents who are in dire need of effective solutions (4).

The groundbreaking Teen-LABS (Teen Longitudinal Assessment of Bariatric Surgery) study (7), conducted across multiple centers, has significantly contributed to our understanding of bariatric surgery outcomes in adolescents. Key findings from this study and others include: (I) adolescents who undergo bariatric surgery experience substantial and sustained long-term weight loss, comparable to adults, with higher remission rates for type 2 diabetes and hypertension (8,9). (II) Long-term follow-up data demonstrate that weight reduction persists beyond the initial post-operative period, leading to improvements in metabolic parameters such as insulin sensitivity and lipid profiles (9,10). (III) Contrary to prevailing assumptions, certain mental health outcomes such as eating disorders (11), binge eating disorder (12), and depression are generally favorable after bariatric surgery (13). Adolescents report improved self-esteem, reduced depression and anxiety, and enhanced quality of life (14). Importantly, these improvements are not overshadowed by the challenges associated with significant weight loss. While any surgical procedure carries inherent risks, the benefits of bariatric surgery in adolescents outweigh the potential downsides. Adolescents with severe obesity face a higher risk of cardiovascular disease, type 2 diabetes, and obstructive sleep apnea (15). Bariatric surgery offers a chance to mitigate these risks and improve overall health and quality of life.


Realistic expectations and risk mitigation

As we advocate for the availability of bariatric surgery for pediatric patients, we must emphasize the need for realistic expectations. Pre-operative consultations should candidly discuss mental health outcomes, addressing concerns and dispelling myths. Moreover, patients and their families must be informed about the risks of alcohol use disorder and potential self-harm, ensuring responsible post-operative behavior. Bariatric surgery is not a standalone solution. A multidisciplinary team—including pediatricians, dietitians, psychologists, and surgeons—plays a crucial role in pre-operative assessment, post-operative support, and long-term follow-up. Collaboration ensures holistic care and optimal outcomes.


A call to action

In conclusion, as medical professionals, we should recognize and balance the benefits and risks. Bariatric surgery is not a panacea, but it is a life-saving evidence-based treatment for adolescents trapped in the vicious cycle of severe obesity coupled with disability and myriad of medical complications. Let us champion evidence-based care, advocate for equitable access, and empower our young patients with hope and healing. In summary, bariatric surgery not only addresses metabolic health but also positively impacts adolescents’ mental, emotional well-being, and quality of life. It is essential to consider both clinical and psychosocial aspects when evaluating the suitability of bariatric surgery for adolescents with severe obesity.


Acknowledgments

Funding: None.


Footnote

Provenance and Peer Review: This article was commissioned by the editorial office, Translational Pediatrics. The article has undergone external peer review.

Peer Review File: Available at https://tp.amegroups.com/article/view/10.21037/tp-24-160/prf

Conflicts of Interest: The author has completed the ICMJE uniform disclosure form (available at https://tp.amegroups.com/article/view/10.21037/tp-24-160/coif). G.S. receives consulting fees from Novo Nordisk, Eli Lilly, and Rhythm Pharmaceuticals, receives research grant support from Eli Lilly, and is on the Speaker’s Bureau for Rhythm and Novo Nordisk. The author has no other conflicts of interest to declare.

Ethical Statement: The author is accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.


References

  1. Bruze G, Järvholm K, Norrbäck M, et al. Mental health from 5 years before to 10 years after bariatric surgery in adolescents with severe obesity: a Swedish nationwide cohort study with matched population controls. Lancet Child Adolesc Health 2024;8:135-46. [Crossref] [PubMed]
  2. Courcoulas AP, Daigle CR, Arterburn DE. Long term outcomes of metabolic/bariatric surgery in adults. BMJ 2023;383:e071027. [Crossref] [PubMed]
  3. Hampl SE, Hassink SG, Skinner AC, et al. Executive Summary: Clinical Practice Guideline for the Evaluation and Treatment of Children and Adolescents With Obesity. Pediatrics 2023;151:e2022060641. [Crossref] [PubMed]
  4. Pratt JSA, Browne A, Browne NT, et al. ASMBS pediatric metabolic and bariatric surgery guidelines, 2018. Surg Obes Relat Dis 2018;14:882-901. [Crossref] [PubMed]
  5. Twig G, Yaniv G, Levine H, et al. Body-Mass Index in 2.3 Million Adolescents and Cardiovascular Death in Adulthood. N Engl J Med 2016;374:2430-40. [Crossref] [PubMed]
  6. Hales CM, Carroll MD, Fryar CD, et al. Prevalence of Obesity and Severe Obesity Among Adults: United States, 2017-2018. NCHS Data Brief 2020;1-8. [PubMed]
  7. Michalsky MP, Inge TH, Teich S, et al. Adolescent bariatric surgery program characteristics: the Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study experience. Semin Pediatr Surg 2014;23:5-10. [Crossref] [PubMed]
  8. Inge TH, Courcoulas AP, Helmrath MA. Five-Year Outcomes of Gastric Bypass in Adolescents as Compared with Adults. N Engl J Med 2019;381:e17. Reply. [Crossref] [PubMed]
  9. Inge TH, Jenkins TM, Xanthakos SA, et al. Long-term outcomes of bariatric surgery in adolescents with severe obesity (FABS-5+): a prospective follow-up analysis. Lancet Diabetes Endocrinol 2017;5:165-73. [Crossref] [PubMed]
  10. Järvholm K, Janson A, Peltonen M, et al. Metabolic and bariatric surgery versus intensive non-surgical treatment for adolescents with severe obesity (AMOS2): a multicentre, randomised, controlled trial in Sweden. Lancet Child Adolesc Health 2023;7:249-60. [Crossref] [PubMed]
  11. Taba JV, Suzuki MO, Nascimento FSD, et al. The Development of Feeding and Eating Disorders after Bariatric Surgery: A Systematic Review and Meta-Analysis. Nutrients 2021;13:2396. [Crossref] [PubMed]
  12. Kubik JF, Gill RS, Laffin M, et al. The impact of bariatric surgery on psychological health. J Obes 2013;2013:837989. [Crossref] [PubMed]
  13. Law S, Dong S, Zhou F, et al. Bariatric surgery and mental health outcomes: an umbrella review. Front Endocrinol (Lausanne) 2023;14:1283621. [Crossref] [PubMed]
  14. Goldenshluger A, Maor T, Via-Kagan R, et al. Short-Term Changes in Mental, Physical, and Social Factors After Metabolic Bariatric Surgery in Adolescents: A Nationwide Prospective Cohort Study. Front Nutr 2022;9:878202. [Crossref] [PubMed]
  15. Zeller MH, Inge TH, Modi AC, et al. Severe obesity and comorbid condition impact on the weight-related quality of life of the adolescent patient. J Pediatr 2015;166:651-9.e4. [Crossref] [PubMed]
Cite this article as: Srivastava G. Bariatric surgery in adolescents—a vital treatment option. Transl Pediatr 2024;13(8):1287-1289. doi: 10.21037/tp-24-160

Download Citation