Original Article

Clinical and prognostic significance of initial fever in children with Langerhans cell histiocytosis

Na Li, Ying Yang, Zhihua Gong, Hongyun Lian, Honghao Ma, Yali Liu, Xiaolu Nie, Dong Wang, Li Zhang, Ang Wei, Lei Cui, Liping Zhang, Wenxin Ou, Yizhuo Wang, Wanshui Wu, Tianyou Wang, Zhigang Li, Rui Zhang

Abstract

A portion of children with Langerhans cell histiocytosis (LCH) exhibit recurrent or persistent disease-related fever at their first visit. We aimed to clarify the clinical characteristics, laboratory indicators, prognostic differences, and optimal regimens for these children with fever.

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