Vol 15, No 8 (August 31, 2026): Translational Pediatrics

Editorial Commentary

Automated oxygen control in extremely preterm infants: lessons from a negative trial
Bianca C. Benincasa, Rita C. Silveira
Translational Pediatrics  
2026;
15
(8)
:295
.
Influenza vaccination in children with underlying conditions: affirming effectiveness and confronting gaps
Kimberley H. Geissler, Elizabeth Peacock-Chambers
Translational Pediatrics  
2026;
15
(8)
:296
.
Is blood benign?—current evidence on perioperative pediatric transfusion
Whitman B. Wiggins, Heather Liebe, Ana R. Do, Janice A. Taylor, Shawn D. Larson, Izabela Oluwole, Reema Kashif, Steven L. Raymond
Translational Pediatrics  
2026;
15
(8)
:297
.
Beyond screen time: rethinking social media as a developmental context for adolescent well-being
Jean-Philippe Chaput, Hugues Sampasa-Kanyinga
Translational Pediatrics  
2026;
15
(8)
:298
.

Original Article

Is there an association between dietary fiber intake, screen time, and physical activity among students aged 14 to 17 years?—a cross-sectional study
Carla Greier, Clemens Drenowatz, Jozsef Dudas, Gerhard Ruedl, Markus Posch, Klaus Greier
Translational Pediatrics  
2026;
15
(8)
:299
.
Outcomes after surgical management of anomalous aortic origin of a coronary artery (AAOCA): an up-to-date systematic review and meta-analysis
Giuseppe Imperatore, Mauro Lo Rito, Giuseppe Scrascia, Lorenzo Giovannico, Luca Savino, Giuseppe Fischetti, Giovanni Meliota, Danila Azzolina, Christoph Gräni, Tomaso Bottio, Massimo A. Padalino
Translational Pediatrics  
2026;
15
(8)
:300
.
Stage-associated differences in injury and stress responses of hiPSC-derived cardiomyocytes under macrophage-derived inflammatory stimulation
Wei Jing, Qingbin Liu, Xiaoyi Chang, Yuna Zhang, Jing Li
Translational Pediatrics  
2026;
15
(8)
:301
.
Association between 24-hour urine output during early non-invasive ventilation and short-term adverse outcomes in late preterm infants: a retrospective cohort study
Ling Lu, Xiuxia Zhang
Translational Pediatrics  
2026;
15
(8)
:302
.
Admission SpO2/FiO2 ratio for mortality risk stratification in children with severe pneumonia: a multicenter retrospective cohort study
Huiling Zhang, Zhenjie Chen
Translational Pediatrics  
2026;
15
(8)
:303
.
Inflammatory marker profiles in immunocompetent hospitalized children with adenovirus infection and association with hospitalization outcomes
Zixuan Wang, Yuanjie Zhou, Yajuan Zhou, Lijuan Luo, Qing Cao
Translational Pediatrics  
2026;
15
(8)
:304
.
Stakeholder perspectives on managing insulin pump-related skin complications in children with type 1 diabetes: a mixed methods study in China
Ting Yuan, Meiying Gao, Chuhao Zhang, Lejing Guan, Yan Zheng, Junfen Fu, Guanping Dong, Wei Wu, Ke Huang, Xiaochun Chen, Guannan Bai
Translational Pediatrics  
2026;
15
(8)
:305
.
Endoplasmic reticulum stress-mediated disruption of mitochondrial homeostasis drives airway epithelial barrier fragility and enhances susceptibility to recurrent respiratory tract infections in children
Xiaoyi Chang, Wei Jing, Qingbin Liu, Xueli Wu
Translational Pediatrics  
2026;
15
(8)
:306
.
Development and validation of an early warning score for refractory Mycoplasma pneumoniae pneumonia in pediatric patients
Dani Qin, Mengke Cheng, Xujiao Pu, Lingyun Xia, Xueping Zhu
Translational Pediatrics  
2026;
15
(8)
:307
.
Establishing a nomogram model for predicting hospital length of stay in children with II–III degree scald burns based on admission assessment indicators
Ying Gao, Biyun He, Jing Huang, Yang Pan
Translational Pediatrics  
2026;
15
(8)
:308
.
Clinical factors associated with extrapulmonary complications in children with macrolide-resistant Mycoplasma pneumoniae pneumonia: a single-center retrospective matched case-control study
Tianfu Xu, Seyan Yan, Saiping Huang
Translational Pediatrics  
2026;
15
(8)
:309
.
Decreased H3K79 acetylation and dysregulation of neurodevelopmental genes in fetal down syndrome
Shuai Ye, Baoling Bai, Zhuran Zhao, Li Wang, Qing Mu, Yang Zhang, Xinjuan Wang, Ting Zhang, Weidong Yu, Jingzhu Guo
Translational Pediatrics  
2026;
15
(8)
:310
.
Histone acetylation-regulated FBXO11-dependent degradation of BLIMP-1 promotes lung injury
Bangzhi Sui, Yingying Wang, Jie Liu
Translational Pediatrics  
2026;
15
(8)
:311
.
Development and validation of a risk prediction model for respiratory tract Ureaplasma urealyticum infection in preterm infants
Jinju Shi, Huiyue Zhang, Yanni Xu, Hongzhu Cai, Shaoru Zheng, Cuimin Su
Translational Pediatrics  
2026;
15
(8)
:312
.
Ultrasound-based nomogram for predicting high-risk hepatic portal venous gas in children: a retrospective cohort study
Chao Ma, Pengling Huang, Guanghua Pei, Zhaowei Meng
Translational Pediatrics  
2026;
15
(8)
:313
.
Clinical characteristics and prognosis of infant onset inflammatory bowel disease in Chinese children: a 10-year single-center experience
Junye Du, Dexiu Guan, Xiaolin Ye, Tianzhuo Zhang, Jie Wu
Translational Pediatrics  
2026;
15
(8)
:314
.
Association between childhood weight status and timing of puberty: a systematic review and meta-analysis
Ting Zhou, Feng Xiong
Translational Pediatrics  
2026;
15
(8)
:315
.
A taurine metabolism-related gene program defines clinical and biological features of neuroblastoma and yields an 8-gene candidate prognostic model
Benfu Zhong, Yanan Zhang, Zhaosong Wang, Qiuping Dong, Xin Li, Yuren Xia
Translational Pediatrics  
2026;
15
(8)
:316
.
Development and validation of a multivariate predictive model for the risk of refractory mycoplasma pneumoniae pneumonia in children based on quantitative computed tomography features
Lei Wang, Tian Hu, Yu Lei, Tao Ren, Shunlin Guo
Translational Pediatrics  
2026;
15
(8)
:317
.
Development and bootstrap-based internal validation of a dynamic model for predicting acute kidney injury after day-3 reassessment in children with severe community-acquired pneumonia
Jing Dong, Jing Yue, Hui Zhao, Ling Jiang
Translational Pediatrics  
2026;
15
(8)
:318
.
Predictive value of neutrophil-to-lymphocyte ratio and fibrinogen degradation products for renal involvement in pediatric immunoglobulin A vasculitis
Guangbo Li, Jianying Liao, Zhuqin Zhan, Jinhua Zeng, Dequan Su
Translational Pediatrics  
2026;
15
(8)
:319
.
Development of a machine learning-based assistive diagnostic model for Epstein‑Barr virus‑associated hemophagocytic lymphohistiocytosis in pediatric patients
Sheng-Quan Guo, Ying Tian, Yu-Feng Zhang, Hui-Ling Deng, Xi-Ru Yang, Min Han, Lu Cao, Peng-Fei Xu, Xiao-Yan Wang
Translational Pediatrics  
2026;
15
(8)
:320
.
Risk factors and construction of prediction model for plastic bronchitis in children with Mycoplasma pneumoniae pneumonia
Rui Xin, Xinhui Yuan, Juntao Jin, Jing Shu, Xinhua Ye
Translational Pediatrics  
2026;
15
(8)
:321
.
Clinical determinants of severe vaso-occlusive crisis in pediatric sickle cell anemia: a retrospective cohort study
Ebtihal Elameen Eltyeb, Sami Abdu Alhazmi, Hussain Ahmed Moafa, Gassem Ali Gohal, Mohammed Ali Alqassim, Reham Mohammad Ghobin, Yasir Alhijab M. Kadi, Atyaf Abdullah Ali Madkhali, Raed Mohammed Ahmed Ahmed, Afnan Hussain Ahmed Abuzawah, Abdulrahman Mohammad Abdulrahman Abutalib, Remaz Ramay Atifa Ramily, Sharifah A. Komeit, Sawsan A. Rifaei, Husam Mohammed Fadhali
Translational Pediatrics  
2026;
15
(8)
:322
.
Evaluating the risk of elevated IL-6 levels in pediatric patients: a stratified approach and evidence of interaction effects
Xun Li, Haipeng Yan, Xiao Li, Enmin Li, Ting Luo, Xiangyu Wang, Longlong Xie, Yufan Yang, Xinping Zhang, Jiaotian Huang, Zhenghui Xiao
Translational Pediatrics  
2026;
15
(8)
:323
.
Radiofrequency ablation for severe hemangiomas with thrombocytopenia and coagulation abnormalities (Kasabach-Merritt phenomenon)
Junjie Lin, Bin Fang, Wenting Jiao, Changkuan Chen, Yaqing Ding, Gaozan Zhu, Wenqiu Wang, Wenbo Liu, Hua Xiang, Junbo Qiao
Translational Pediatrics  
2026;
15
(8)
:324
.
Decisional conflict levels and associated factors among parents of pediatric patients undergoing emergency gastric lavage: a cross‑sectional survey
Ying Meng, Ran Li, Hongzhi Zhou, Dan Chen
Translational Pediatrics  
2026;
15
(8)
:325
.
Cohen versus Lich-Gregoir ureteral reimplantation for pediatric primary vesicoureteral reflux: a systematic review and meta-analysis of comparative studies
Bowen Liang, Jiayi Li, Ke Xu
Translational Pediatrics  
2026;
15
(8)
:326
.
The dose-effect relationship between red blood cell transfusion volume and adverse events in pediatric cardiac surgery
Wenting Wang, Qindong Liu, Tianyu Gao, Yu Jin, He Wang, Jia Liu, Bingyang Ji, Jinping Liu
Translational Pediatrics  
2026;
15
(8)
:327
.
Clinical outcomes and determinants of intraoperative hyperlactatemia in neonates undergoing gastrointestinal surgery: a retrospective cohort analysis
Tingyi Lv, Jialian Zhao, Chunyi Jin, Binbin Cai, Yaoqin Hu, Yue Jin
Translational Pediatrics  
2026;
15
(8)
:328
.
A machine learning-based early in-hospital risk stratification model for severe mycoplasma pneumoniae pneumonia in children
Weichun Li, Tingting Xu, Rui Xin, Tao Yan, Xu Yang
Translational Pediatrics  
2026;
15
(8)
:329
.
Whole-exome sequencing-centered genetic evaluation for early-onset obesity in Chinese children: a retrospective single-center cohort
Si Chen, Jing Zhang, Liyuan Ge, Zhonghui Li, Liuxu Wang, Xinran Cheng
Translational Pediatrics  
2026;
15
(8)
:330
.
Factors associated with in-hospital mortality and treatment withdrawal in mechanically ventilated children with severe pneumonia: a retrospective cohort study
Nandu Luo, Hui Li, Guangyue Luo, Fei Wang, Shuanglin Li, Lijun Zhang
Translational Pediatrics  
2026;
15
(8)
:331
.
A multicenter prospective evaluation of a decision chart for toilet training initiation
Chisato Oyake, Yoshitaka Watanabe, Noriko Ueda, Akiko Tange, Sachiko Nozawa, Hirokazu Ikeda
Translational Pediatrics  
2026;
15
(8)
:332
.
Gut microbiota alterations in Neonatal Intensive Care Unit extremely preterm infants: a Chinese tertiary center study
Weijuan Han, Peipei Fu, Hong Cui
Translational Pediatrics  
2026;
15
(8)
:333
.
Retrospective analysis of platelet to high-density lipoprotein cholesterol ratio in obese children with metabolic dysfunction-associated fatty liver disease
Gang Li, Chen Wang, Weixia Yang
Translational Pediatrics  
2026;
15
(8)
:334
.
Efficacy and safety of application of Sivelestat in pediatric intensive care unit: a systematic review and meta‑analysis
Cai-Xia Tu, Jian-Ling Shen, Dan-Yang Ren, Yun-Wei Li, Qiong Zou, Yan-Ming Yang, Hui-Ying Li
Translational Pediatrics  
2026;
15
(8)
:335
.
Early mortality-associated factors in pediatric fulminant myocarditis patients treated with venoarterial extracorporeal membrane oxygenation: a single-center retrospective cohort study
Huiling Zhang, Sheng Ye, Zihao Yang
Translational Pediatrics  
2026;
15
(8)
:336
.
Traditional Chinese medicine combined with conventional Western medicine for chronic cough following respiratory infection in children: a systematic review and meta-analysis
Shengtao Cui, Xiaofei Xie, Jingjing Yang, Yao Xiao, Wei Wang
Translational Pediatrics  
2026;
15
(8)
:337
.
Development and validation of a prediction model for 6-month early death in pediatric H3K27M-mutant diffuse intrinsic pontine glioma (DIPG)
Long Wang, Xiaohao Liu, Yanan You, Yue Yu, Dandan Wang, Jiayao Xu, Boya Zhang, Juan Wang, Yingjuan Zheng
Translational Pediatrics  
2026;
15
(8)
:338
.
The global landscape of pediatric hyperuricemia research: a bibliometric roadmap to mechanisms, management, and future therapeutics (1997–2024)
Liang Xiao, Wei Lu, Junli Wang, Shengyou Yu
Translational Pediatrics  
2026;
15
(8)
:339
.
Diagnostic and therapeutic value of double-balloon enteroscopy in pediatric patients with Peutz-Jeghers syndrome
Wei-Chen Shen, Zhu-Bin Pan, Shi-Qin Qi, Jun-Jun Ju, Yu-Liang Zhou, Tao Zhang, Zhen-Qiang Zhang
Translational Pediatrics  
2026;
15
(8)
:340
.
Construction of a prediction model for retinopathy of prematurity based on placenta-derived genes and clinical variables
Dan Huang, Rong Gan, Yunpeng Zhang, Zikang Chen, Yang Bai, Weifeng Zhu, Daya Luo, Yulan Yang, Zhuoqi Liu, Yan Deng
Translational Pediatrics  
2026;
15
(8)
:341
.
Obesity-related palmitic acid exacerbates IL-13-induced mucus phenotype in 16HBE airway epithelial cells via AMPK suppression
Qingbin Liu, Xiaoyi Chang, Wei Jing, Siyu Liu
Translational Pediatrics  
2026;
15
(8)
:342
.
Predictive value of the prognostic nutritional index and aggregate index of systemic inflammation for pulmonary complications in children with influenza
Yuanyuan Wu, Jianjian Zhang, Xuejia Ke, Junping Pan, Yuping Hu
Translational Pediatrics  
2026;
15
(8)
:343
.
Plasma polyunsaturated fatty acids and amino acids in children with attention-deficit hyperactivity disorder: correlations with clinical and cognitive features
Liuyan Zhu, Lei Wang, Tianmiao Gu, Weijun Chen
Translational Pediatrics  
2026;
15
(8)
:344
.
The hypoxic burden algorithm: an integrated index for assessing intermittent hypoxia in pediatric obstructive sleep apnea—a retrospective cohort study
Lingling Zhong, Fanyu Mu, Uul Gegeen, Junmei Zhang, Liang Li, Wei Wang, Guangping Liu, Bei Shen, Shuang Li, Hualei Cui
Translational Pediatrics  
2026;
15
(8)
:345
.

Review Article

Why stop at extubation?—the difference between enhanced recovery and on table extubation after paediatric cardiac surgery
Tim Murphy, Louise Davies, Barny Allan, Tuan Chen Aw
Translational Pediatrics  
2026;
15
(8)
:346
.
Emerging genes implicated in human congenital heart disease: a 2023–2025 scoping review
Shani Israel, Sarah U. Morton
Translational Pediatrics  
2026;
15
(8)
:347
.
Metabolic reprogramming rewires aberrant immune responses to drive endothelial dysfunction in Kawasaki disease: a narrative review
Zixuan Zhao, Shuhui Wang, Xuan Li, Liyan Zhu, Haitao Lv, Guanghui Qian
Translational Pediatrics  
2026;
15
(8)
:348
.
Probiotics in asthma: immunoregulatory mechanisms and emerging opportunities for respiratory delivery—a narrative review
Xiaocheng Wu, Yicheng Xie, Yingshuo Wang, Jiani Shan, Jiayao Song, Zhiyuan Lin, Rongrong Pan, Xin Yang
Translational Pediatrics  
2026;
15
(8)
:349
.
How to evaluate, triage, and sedate a patient in the congenital cardiac catheterization laboratory
Eleni Asimacopoulos, Brian Quinn, Kirsten C. Odegard
Translational Pediatrics  
2026;
15
(8)
:350
.
Biomarkers of partial remission in paediatric type 1 diabetes: β-cell stress, immune-metabolic remodelling, and translational priorities—a narrative review
Hu Lin, Wei Wu, Ke Huang, Guanping Dong, Junfen Fu
Translational Pediatrics  
2026;
15
(8)
:351
.

Case Series

Thulium fiber laser cauterization approach to congenital pyriform sinus fistula: a case series
Ying Wang, Chenling Shen, Xiaojun Liu, Jiarui Chen, Xiaoyan Li
Translational Pediatrics  
2026;
15
(8)
:352
.

Case Report

Early-onset type 1 diabetes mellitus in a child with a pathogenic CTLA4 variant complicated by generalized lipodystrophy and severe insulin resistance: a case report and literature review
Yu Ding, Qun Li, Qianwen Zhang, Shiyang Gao, Juan Li, Lingwen Ying, Ru-En Yao, Tingting Yu, Xiumin Wang
Translational Pediatrics  
2026;
15
(8)
:353
.
Molecularly guided management of pediatric endobronchial inflammatory myofibroblastic tumor: a report of two cases on surgical and targeted intervention
Liqin Ke, Shuxian Li, Lei Wu, Guohong Zhu
Translational Pediatrics  
2026;
15
(8)
:354
.
Clinical and modifier gene profiles in reversible infantile respiratory chain deficiency: three Chinese cases report and literature review
Tongyue Li, Chaolong Xu, Zhimei Liu, Yang Liu, Ying Zou, Zimeng He, Yunxi Zhang, Mingxi Sun, Hong Xue, Hua Li, Fang Fang
Translational Pediatrics  
2026;
15
(8)
:355
.
RNA sequencing resolves a novel noncanonical splice-region variant in PHKA2 causing glycogen storage disease type IX α2: a case report
Fan Chen, Jiayi He, Henghui Cheng, Sainan Shu
Translational Pediatrics  
2026;
15
(8)
:356
.